Journal: Biomacromolecules

Article Title: Hyaluronic Acid Nanoparticles with Parameters Required for In Vivo Applications: From Synthesis to Parametrization

doi: 10.1021/acs.biomac.4c00370

Figure Lengend Snippet: Characteristics of nanoparticles. (A) FTIR spectra in the range between 1830 and 1000 cm –1 . Comparison of free HA (red spectrum) and AAD-, BAPA-, EDBE-, and EDA-HANPs. Fractograms obtained by A4F of (B) AAD-HANPs, (C) BAPA-HANPs, (D) EDBE-HANPs, and (E) EDA-HANPs. The TEM images of (F) AAD-HANPs, (G) BAPA-HANPs, (H) EDBE-HANPs, and (I) EDA-HANPs stained with uranyl acetate. (J) SPR binding curves of HANPs and free HA on the CD44-modified CMDP SPR chip. (K) SPR binding curves of AAD-HANPs on the CD44-modified CMDP SPR chip demonstrating the effect of 0.05% Tween 20.

Article Snippet: Planar carboxymethyl dextran (CMDP) surface plasmon resonance (SPR) sensor chips were purchased from XanTec Bioanalytics, Germany.

Techniques: Comparison, Staining, Binding Assay, Modification

Journal: Microchemical Journal

Article Title: Biosensors promising bio-device for pandemic screening “COVID-19“

doi: 10.1016/j.microc.2021.106094

Figure Lengend Snippet: Developed biosensors for the detection of coronaviruses.

Article Snippet: Innovative biosensors used to detect RNA-viruses include nucleic-acid based, CRISPR-Cas9 based paper strips, optical biosensor, aptamer-based, antigen-Au/Ag nanoparticles-based electrochemical biosensors, and Surface Plasmon Resonance (SPR), , .

Techniques: Luciferase, Protein-Protein interactions

Journal: Microchemical Journal

Article Title: Biosensors promising bio-device for pandemic screening “COVID-19“

doi: 10.1016/j.microc.2021.106094

Figure Lengend Snippet: Various type of the biosensors for SARS-CoV-2 virus detection . A) CRISPR based nucleic acid (RNA) detection . B) FET based biosensor operation , C) AuNPs based FTO electrode biosensor , D) Surface Plasmon Resonance (SPR) based biosensor, E) 2D gold Nano-islands (AuNIs) functionalized biosensors .

Article Snippet: Innovative biosensors used to detect RNA-viruses include nucleic-acid based, CRISPR-Cas9 based paper strips, optical biosensor, aptamer-based, antigen-Au/Ag nanoparticles-based electrochemical biosensors, and Surface Plasmon Resonance (SPR), , .

Techniques: Virus, CRISPR, RNA Detection, SPR Assay

Journal: Microchemical Journal

Article Title: Biosensors promising bio-device for pandemic screening “COVID-19“

doi: 10.1016/j.microc.2021.106094

Figure Lengend Snippet: Illustration of proposed SPR based biosensor for detection of coronaviral surface antigen (SCVme), AFM images of the sequential binding of GBP-E-SCVme and anti-SCVme on the gold-micro-patterned surface. (A) Bare gold surface, (B) binding of the GBP-E-SCVme fusion proteins onto the gold surface, and (C) subsequent binding of the anti-SCVme antibodies on the GBP-E-SCVme layer. Left, representation plans for the successive binding of GBP-E-SCVme and anti-SCVme on the gold micro-patterns; middle, three-dimensional topological images; right, the cross-sectional contours of samples a–c, sequentially (these are average height differences of the individual scan lines from each area) .

Article Snippet: Innovative biosensors used to detect RNA-viruses include nucleic-acid based, CRISPR-Cas9 based paper strips, optical biosensor, aptamer-based, antigen-Au/Ag nanoparticles-based electrochemical biosensors, and Surface Plasmon Resonance (SPR), , .

Techniques: Binding Assay

Journal: bioRxiv

Article Title: Neutralizing Antibodies Isolated by a site-directed Screening have Potent Protection on SARS-CoV-2 Infection

doi: 10.1101/2020.05.03.074914

Figure Lengend Snippet: SPR to measure the binding affinity of SARS-CoV-2-RBD-his protein to captured antibodies.

Article Snippet: Surface plasmon resonance (SPR) was performed by GenScript (GenScript, Nanjing) to measure the affinity of the antibody.

Techniques: Binding Assay